Homosildenafil (also known as methyl-sildenafil) is a synthetic drug which acts as a phosphodiesterase inhibitor. It is an analog of sildenafil and vardenafil. Homosildenafil has been first identified in sex enhancement products in 2003 and was more recently detected in dietary supplements.
Homosildenafil has 35% the PDE5 inhibition activity of sildenafil itself with similar selectivity.
