Citroenmelisse om neurotoxiteit van MDMA te verminderen
Geplaatst: vr okt 04, 2013 4:15 pm
Pubmed schreef:...
Results:
A high dose of ecstasy caused profound mitochondrial dysfunction, around 40% less than the control value, and increased apoptotic neuronal death to around 35% more than the control value in hippocampal neuronal culture. Co-treatment with Melissa officinalis significantly reversed these damages to around 15% and 20% respectively of the MDMA alone group, and provided protection against MDMA-induced mitochondrial dysfunction and apoptosis in neurons.
Conclusion:
Melissa officinalis has revealed neuroprotective effects against apoptosis induced by MDMA in the primary neurons of hippocampal culture, which could be due to its free radical scavenging properties and monoamine oxidase (MAO) inhibitory effects.
Volledig Pubmed artikel: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652537/