Chaincells schreef: maar is vloeibare LSD niet gewoon LSD-kristallen opgelost in water?
LSD-zegels worden gewoon gedruppeld met vloeibare LSD voor zo ver ik weet.
Salientje schreef:lsd vellen mogen niet open en bloot liggen dan vergaan ze heel snel .....
adus wikipedia.Het lost slecht op in water en je moet de zuivere stof voorzichtig behandelen, draag veiligheidshandschoenen en een stofmasker.
Opslag zuivere stof bewaren bij -20°C
again wikipedia.De vrije base lsd lost slecht op in water. Daarom maakte Hofmann een variant, de zogenaamde tartraat-vorm.
(no shit, wikipedia)Een tartraat is een zout of ester van wijnsteenzuur C4H6O6.
Tartraten worden vaak gebruikt als voedingsadditief en fungeren in die zin dikwijls als antioxidant en/of zuurteregelaar.
Drientje schreef:Nergens op internet vind ik bewijs dat LSD een instabiele stof is.
Chaincells schreef:o.0 Dan zou het ook van een zegel af verdampen toch?
LSD is an unusually fragile molecule and some comments are in order as to its stability and storage. As a salt, in water, cold, and free from air and light exposure, it is stable indefinitely. There are two sensitive aspects of its structure. The position of the carboxamide attachment, the 8-position, is affected by basic, or high pH, conditions. Through a process called epimerization, this position can scramble, producing isolysergic acid diethylamide, or iso-LSD. This product is biologically inactive, and represents a loss of a proportionate amount of active product. A second and separate point of instability is the double bond that lies between this 8-position and the aromatic ring. Water or alcohol can add to this site, especially in the presence of light (sunlight with its ultraviolet energy is notoriously bad) to form a product that has been called lumi-LSD, which is totally inactive in man. Oh yes, and often overlooked, there may be only an infinitesimal amount of chlorine in treated tap water, but then there is only an infinitesimal amount of LSD in a typical LSD solution. And since chlorine will destroy LSD on contact, the dissolving of LSD in tap water is not appropriate.
Whether on blotter paper or as a powder, LSD is degraded by three routes: 1) UV Light, 2) heat and 3) free radicals, especially ozone.
A controlled study was undertaken to determine the stability of LSD in pooled urine samples. The concentrations of LSD in urine samples were followed over time at various temperatures, in different types of storage containers, at various exposures to different wavelengths of light, and at varying pH values. These studies demonstrated no significant loss in LSD concentration at 25 degrees C for up to 4 weeks. After 4 weeks of incubation, a 30% loss in LSD concentration at 37 degrees C and up to a 40% at 45 degrees C were observed. Urine fortified with LSD and stored in amber glass or nontransparent polyethylene containers showed no change in concentration under any light conditions. Stability of LSD in transparent containers under light was dependent on the distance between the light source and the samples, the wavelength of light, exposure time, and the intensity of light. After prolonged exposure to heat in alkaline pH conditions, 10 to 15% of the parent LSD epimerized to iso-LSD. Under acidic conditions, less than 5% of the LSD was converted to iso-LSD. There was also demonstrated that trace amounts of metal ions in buffer or urine could catalyze the decomposition of LSD and that this process can be avoided by the addition of EDTA.
Drientje schreef:Maar is wat je op je blottertje hebt 100% zuivere stof?
Dus hij maakte er een kristal van? Is de LSD op mijn zegeltjes de tartraat vorm of de slecht in water oplosbare?
Ik vind niet echt een antwoord op deze vragen op internet.
For the fraction containing the LSD, conversion to LSD tartrate must be done to make it water soluble, improve its keeping characteristics, and to allow crystallization. Tartaric acid has the ability to react with two molecules of LSD. Use, then, of a 50% excess of tartaric acid dictates the use of about 1 gram of tartaric acid to 3 grams of LSD. The three grams of LSD would be expected from a well-done batch out of a total 3.5 LSD/iso-LSD mix.
First of all, I would like to point out that I am an x-ray crystallographer. My who job consists of crystallizing molecules. When I worked in organic synthesis, we used crystallization as a purification technique. When it comes to biomacromolecules, crystallization is much more difficult and you are far more likely to come across polymorphs.
It is entirely possible to have two very different looking crystals of the same substance with essentially the same purity, just as it is entirely possible to have two similar looking crystals of the same substance with very different purity. You can't tell just by looking!
However, even LSD is known to show crystal polymorphism. This means that, absolutely pure LSD tartrate exists in more than one crystal form.
Furthermore, I will say this. The idea that someone can tell crystal purity by visual inspection alone is complete and utter bullshit. I have seen substances that usually crystallize into beautiful pure white crystals precipitate as purple coloured garbage under the exact same conditions (as far as I can control for, at least). Of course, my first thought upon seeing something like that, is "Oh, my sample sucks. I may as well get rid of it." Further analyses can be very surprising. In this case, it was less than 2% impurity disrupting the crystallization process and adding the purple colour.
I have also seen beautiful crystal that give such garbage diffraction patterns that the purity must have been far below 50%, even though the crystal looked just like the pure ones that gave good diffraction data.
I suggest that you take the "needlepoint, fluff, etc." reports with more than a few grains of salt. It's complete nonsense.
After it has been collected, strip the remaining material from the column by washing
with MeOH. Use the UV light sparingly to prevent excessive damage to the compounds. Evaporate the second fraction in vacuo and set aside for Step II. The fraction containing the pure LSD is concentrated in vacuo and the syrup will crystallise slowly. This material may be converted to the tartrate by tartaric acid and the LSD tartrate conveniently crystallised. MP 190-196 C.
The simplest form of LSD is called the "free base" which means that it is just the LSD molecule itself with no stabilizing salt. The LSD sold on blotter or in other forms on the street is often 'attached' to a salt. One of the most common forms is LSD tartrate, or an LSD molecule with tartaric acid acting to make it a salt.
Delysid (LSD 25) - D-lysergic acid diethylamide tartrate
Sugar-coated tablets containing 0.025 mg. (25 µg)
Ampoules of 1 ml. containing 0.1 mg. (100 µg) for oral administration
The solution may also be injected s.c. or i.v. The effect is identical with that of oral administration but sets in more rapidly.
Crystallization of the tartrate usually begins as soon as the tartaric acid dissolves completely. The beaker and contents are refrigerated for at least four hours. Occasional stirring of the crystallizing solution will produce smaller crystals, whereas if the solution is left unstirred during the crystallization, larger crystals will grow.
Tablets and pieces of blotter normally contain between 20 and 200 ug of LSD tartrate.
Chaincells schreef:LSD-zegels worden gewoon gedruppeld met vloeibare LSD voor zo ver ik weet.
One of the principal purposes of selling or distributing LSD in aqeuos solutions is to facilitate the "blotting" or soaking of LSD paper. These small containers are purported to have enough LSD to properly soak from 100 to 1000 dosage units. Dealers intent on manufacturing their own blotter paper will experiment to determine how much solvent is required to wet a piece of paper equal to the desired number of dosage units. The LSD solution in the small bottle is then diluted to this "experimental" volume and applied to the paper. Using this process LSD is distributed more or less uniformly over the whole sheet of paper. After the solvent(s) have evaporated, the LSD particles adhere to all the fibers of the sheet of paper making a durable form for sale or distribution."
Salientje schreef:wel interessant maar vellen worden worden gedrenkt en dan gedroogd.
anders moet een laag loon land ze drippen en net zoals de garnalen ff open neer naar Marokko.
First dump the solution in the pan and dip each tenpack into it then lift it up and let any excess solution run off into the pan. Second method is to put the tenpack into the pan and squirt the solution on it with a baby syringe(the ones they give little kids medicine with). I Have done both and prefer dipping them just because its quicker.
However, haphazard dipping, per se, is not the most common way of applying LSD/solvent to paper. Such ungoverned dipping has two drawbacks: first, valueable LSD solution is lost from paper when too much liquid is applied since it often drips off, and second, there is a real possibility of an accidental overdose for the person manipulating the paper. Most large-scale blotting operations attempt to "calibrate" the paper they are using. This is accomplished through experimentation in order to determine how much solution is required to wet the paper up to the edges through the phenomenon of capillary action. The paper is then "laid" out in the orientation in which it will be dried. Next the "calibrated" amount of LSD solution is applied. Often a large syringe or pippette, with or without a hose on the end to direct the liquid stream, is used to both measure the solution and apply the "calibrated" amount.
Chaincells schreef:Heb trouwens ook een documentaire gezien waarin iemand LSD druppelde op snoep, (tumtum-achtige structuur). En dat ook gewoon met de post stuurde. Ik ben geen expert verder, maar is vloeibare LSD niet gewoon LSD-kristallen opgelost in water? (andere vloeistof, die verdampt). LSD-zegels worden gewoon gedruppeld met vloeibare LSD voor zo ver ik weet.
Ben nu ook wel erg benieuwd!
Exceptional Insight schreef:Ik vind het altijd leuk dat er naar bronnen gevraagd wordt. En er dan hele lappen tekst aan wetenschappelijke zwendel wordt gedeeld. Maar wat als jouw eigen ervaring anders leert? Geloof je dan nog steeds de onderzoeken?
Exceptional Insight schreef:Ik heb al een paar jaar een stapeltje maya's (180µg) in de kast liggen. Wel wat aluminiumfolie er omheen. Maar vaak een beetje, uit gemakzucht/luiheid er maar wat omheen gefrommeld.
Ik heb nooit iets van kwaliteitsverlies gemerkt.
Intoxication schreef:idd 1 korte uitleg in 1 zin is voldoende info wat ben ik allemaal met die prulinformatie in een taal dat ik niet ken
An unopened, brown-glass vial of 1951 Sandoz LSD-25 (Delysid) was contributed to a gathering in celebration of Albert Hofmann's 100th birthday. The vial had been in the possession of a single person for the last 30+ years, stored casually, mostly in darkness. When opened, the powder was a very light brown-sugar to salmon color. One chemist described the fluffy, clumpy, sparkly crystalline powder as looking like "crushed needles". It was weighed and dissolved into four-ounce liquid doses containing between 100 and 110 micrograms each (± 10%).
Storage & Degradation
Although the vial was completely sealed, without cracks, one of the major questions was whether there would be significant loss of potency by degradation as a result of the 55 years that had passed since it was manufactured. After trying it, the predominant opinion among the more than 70 participants and observers was that there was no detectable loss in potency. This was the clearest result from the reported experiment: air-tight brown glass appears to be a very effective long-term storage method for LSD. After 55 years, stored at varying room temperatures, the LSD seemed to be fully potent.
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