Fig 3 Metabolism of MDMA in man. CYP2D6 Cytochrome P450 2D6, CYP3A4 cytochrome P450 3A4, COMT catechol-O-methyltransferase. This is adapted from de la Torre et al. (2004)
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Zoals te zien is, is onze grote vriend CYP3A4 weer van de partij
Wiki Bluelight.ruGrapefruit Juice
Grapefruit juice inhibits CYP3A4, which is an enzyme in your digestive system that aids in the metabolism of many drugs. By inhibiting CYP3A4, you are essentially making more MDMA available. Although there is some debate as to what exact component(s) of grapefruit juice have this effect, it is accepted that something in there does the job.
Information on the effects of grapefruit juice can be found here
Ik raad iedereen aan die grapefruit overweegt om ook eens dit artikel te lezen:
Grapefruit juice as a "drug booster": don't try this at home
