Noopept (Russian: Ноопепт; GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic remedy. It is derived from the racetam family of drugs and shares similar mechanisms of action,[1][2] but is between 1000 to 5000 times more potent than the prototypical racetam drug, piracetam.[3] Animal studies have shown noopept to be neuroprotective and enhance memory in various tests.[4][5][6][7][8] Unusually for a peptide-derived compound, noopept displays both high oral bioavailability[9] and good blood-brain barrier penetration[10] in rats (although a previous study concluded that "GVS-111 itself was not found in rat brain 1 h after 5 mg/kg i.p. administration up to limit of detection" and that administration of Noopept only increases the concentration of endogenous nootropic Cyclo-L-prolylglycine[2]), and human studies have shown promising results, with potential application in the treatment of Alzheimer's disease.[11] It is also an "immunocorrector" in mice.[12]
It has been found to stimulate the expression of NGF and BDNF in rat hippocampus.
(bron: wikipedia)
Heeft er iemand ervaring mee? Het lijkt wel interessant aangezien het vele malen meer potent is dan piracetam..
merkte niet iets verschillend (met speed). Ben er inmiddels wel mee gestopt, het effect leek een beetje minder te worden. Daarnaast ging na een tijd m'n ooglid een aantal dagen heel enthousiast trillen en dat vond ik een beetje hinderlijk worden, weet trouwens totaal niet zeker of dat wel de schuld van de noopept was (: