Selem schreef:Tripkipje schreef:Ik kan zo snel niet vinden of 3-MMC op de serotonine werkt? Wil dit binnenkort gaan testen maar heb ongeveer een maand geleden 4-FA gehad. Kan ik t beter laten of geen probleem?
Het werkt op de serotonine. Ik weet alleen niet zeker of het een reuptake inhibitor is of ook een releaser....
Grote kans dat het qua werking lijkt op 4-MMC, daar 'weten' we het volgende van (5-HT = serotonine, DA = dopamine) :
Mephedrone as a substituted b-ketoamphetamine is
expected to act primarily by increasing the release of
monoamines and possibly via inhibition of their re-uptake
(Schifano et al., 2011). The major finding of the present study
is that mephedrone causes significant, rapid and dose-
dependent increases in both 5-HT and DA levels in the NAcc.
The overall effects of mephedrone injected at a higher dose
on the 5-HT levels were comparable to the effects induced by
the same dose of MDMA. Both mephedrone and MDMA
preferentially increased 5-HT over the DA levels; however, the
proportion of 5-HT increase (ratio 5-HT : DA) was at least two
times higher for MDMA than for mephedrone. In addition,
mephedrone but not MDMA, still potently increased the
accumbal DA release to a level that was comparable to the
effect induced by amphetamine. Amphetamine had only a
minor effect on extracellular 5-HT concentrations.
http://www.thblack.com/links/RSD/BritJP ... edrone.pdf
Ik zou het in ieder geval als zodanig behandelen, zit je sowieso 'goed'.
